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Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53
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Additionally, studies have pointed to the effect of BH4 inhibiting ferroptosis in T cells, and when the rate-limiting enzyme GCH1 of BH4 is deficient, it will inhibit the proliferation of T cells (159) ( Figure 3 )
We further investigated differentially expressed genes in different groups of comparisons and found that genes are mainly upregulated under mrps-5 RNAi compared to the control
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