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GIP is released from intestinal K cells when glucose and dietary fats enter the small intestine

This can be exacerbated by high toxin levels

Kido J, Haberle J, Sugawara K, Tanaka T, Nagao M, Sawada T, et al

Encouraging outcomes have been observed when MET and PD-1/PD-L1 inhibitors are combined, especially in tumors where MET imbalance leads to increased PD-L1 expression