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Autologous hematopoietic stem cell transplants have been performed in a few cystinosis patients based upon the premise that tunneling nanotubes transport lysosomes bidirectionally between the stem cells and the patients parenchymal cells [158]

Although the K D value for KAR binding of ShHTL1 (77 M) was higher than the physiological concentration (1 M), this result might be because the fraction of active protein in the sample was lower than 100%, resulting in lower estimated affinity than real affinity