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In a market dominated by blockbuster GLP-1 drugs with headline-grabbing weight-loss numbers, a weight-maintenance story, particularly from a 45-patient study, may be harder to value
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This mechanism converges with the previously detailed inflammatory mechanisms, particularly those mediated by pro-inflammatory cytokines, and the increase in adiposity, representing a shared pathological link between metabolic dysfunction and skeletal muscle impairment
Gen Comp Endocrinol 2019;270:75-81
Statistical analysis The data are shown as the mean and standard deviation
Retatrutide is a synthetic investigational peptide designed to act as a triple agonist, targeting the GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors
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