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GIP (Glucose-dependent Insulinotropic Polypeptide): Enhances insulin release in response to meals and synergizes with GLP-1 to improve metabolic response
More importantly, these modified GLP-1 analogues have shown hypoglycemic [185, 186] and cardiovascular protective effects [180, 183] in different animal models
The Phase 2 readout's lack of plateau at 52 weeks is the first clinical signal this hypothesis has merit
Randomization was performed by the principal investigator at the end of baseline testing using sex-stratified tables
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