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It's poly genetic

As a result, Vyvanse improves attention span, controls hyperactivity, and improves mood, says Yusra Jamal, MD, a board-certified endocrinologist at Northwell Long Island Jewish Forest Hills in New York City

Typically, those who should avoid GLP-1s are those with: A personal or family history of certain thyroid cancers Multiple endocrine neoplasia syndrome type 2 A history of pancreatitis Severe gastroparesis (delayed stomach emptying) Pregnancy or plans to become pregnant Additionally, if you have a history of eating disorders, severe depression or unrealistic weight loss expectations, its important to address these concerns with your physician before considering medication

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GLP-1 Body Composition Changes What Trials Show About Lean Mass Clinical trials of semaglutide and tirzepatide consistently demonstrate that effective GLP-1 weight loss reduces both fat and lean mass , with fat making up the majority of the loss (DXA substudies)

These predispositions can support provider conversations about realistic expectations and treatment optimization, but do not predict exact medication response