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Mojic M, Takeda K, Hayakawa Y
A randomized trial investigating the pharmacokinetics, pharmacodynamics, and safety of subcutaneous semaglutide once-weekly in healthy Male Japanese and Caucasian subjects
Assessing MCAS In many cases, MCAS is a clinical diagnosis
More clinical evidence can be found on the role of GLP1R agonists such as exenatide can improve vascular endothelial dysfunction in diabetic patients, as has been found in this clinical trial by Hu et al., results suggested that exenatide improved the endothelial dysfunction reflected by digital reactive hyperemia index in newly diagnosed patients with T2DM, and the effect was not inferior to single metformin [59]
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