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The Journal of Biochemistry, 175 (5), 473-480

Although not traditionally believed to be a CYP450 enzyme involved in paracetamol oxidation, it may be that possession of this allele allows CYP3A5 to use paracetamol as a substrate and hence enhance its bioactivation with resultant liver injury

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Acknowledgements This study was supported by grants from the National Science Foundation for Distinguished Young Scholars of China (no

Guyton explained

Patients should verify whether their clinic dispenses approved drugs or compounded alternatives