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La administracin perifrica de LIRA se sigue de su localizacin a nivel de los rganos circunventriculares y el ncleo arcuato hipotalmico, donde favorece la activacin de vas anorexignicas e inhibicin de las orexignicas, merced a la estimulacin de neuronas productoras de Pro-opiomelanocortina/Transcripto cocana-anfetamina (POMC/CART) y la inhibicin indirecta del eje orexiante NeuropptidoY/Protena relacionada con Agouti (NPY/AgRP) a travs de mecanismos gabargicos18
References : [1] Mun Y, Kim W, Shin D
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By working with the bodys natural hormones, they help reduce hunger, control blood sugar, and support sustainable weight loss
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