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For example, DNA promoter hypomethylation-mediated transcriptional activation of the proto-oncogenes FOXO3, ZEB2 and CDK6 can drive lymph node metastasis and invasion in PTC [152]
Pickarts 2018 review references wrinkle volume reductions up to 55.8%
10.1111/jcmm.14164 J
In summary, crotonylation exerts its effects in colorectal cancer through multiple mechanisms, involving both histone and non-histone modifications, and influences various aspects such as cellular metabolism, metastasis, and chemotherapy resistance
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