However, pharmacovigilance reporting in public databases is subject to many major limitations, such as heterogeneous reporting, including notoriety and ripple bias, double reporting, the lack of a population denominator or enough clinical detail to enable comparison between agents and over time [20, 22], therefore no causal association link can be inferred from such studies
Many of the strategies that protect hair, adequate protein, comprehensive supplementation, moderate pace of loss, and regular monitoring, also protect these other systems
Another limitation is that for thyroid cancer, reporting specifically the cases of MTC vs
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Tirzepatide, which activates both GLP-1 and GIP receptors, may produce different effects compared to pure GLP-1 agonists