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In those using SGLT2i at baseline, 11.0% (143 of 1296) of participants taking semaglutide experienced MACE, compared to 12.2% (158 of 1300) in the placebo group (HR 0.89
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These patients try twice-weekly dosing for 2 to 6 weeks, see no benefit, and return to weekly dosing
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Virmani A et al
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