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Orlistat is indicated as an adjunct in the treatment of obesity, in combination with a hypocaloric diet, for body weight reduction and maintenance of weight loss in adult overweight patients (body mass index [BMI] 28 kg/m) who have obesity-related risk factors, such as high blood pressure, type 2 diabetes, or dyslipidemia

Stop use if irritation occurs

Song Y, Koehler JA, Baggio LL, Powers AC, Sandoval DA, Drucker DJ (2019) Gut-proglucagon-derived peptides are essential for regulating glucose homeostasis in mice

Plasma levels decline significantly with age from approximately 200 ng/ml at age 20 to roughly 80 ng/ml by age 60

Taiwan J Obstet Gynecol

Same pituitary receptor as sermorelin, same downstream GH release