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Excluding patients who already had ESRD, the results showed that LN patients not on GLP-1Ras were twice as likely to progress to ESRD or dialysis dependence within five years compared to those using GLP-1Ras (OR 2.35, 95% CI 1.39, 3.976)

Long-Term and Structural Risks Unregulated Cell Growth (Mitogenic Risk): Like all IGF variants, DES carries a theoretical, but serious, risk of accelerating the growth of existing or dormant cancers (for example, prostate, breast) by stimulating unwanted tissue growth in certain individuals

DiMarchi suspects that the GLP-1 might have reduced damaging inflammation in her brain from her postconcussion syndrome, which played a role in her turnaround

Notably, Ozempic contains a smaller dose of semaglutide compared to Wegovy

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