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The increased use of GLP-1 receptor agonists is particularly striking, most likely due to their beneficial effects on weight reduction

CPT1B is the rate-limiting enzyme in cardiomyocytes that mediates FA transport into mitochondria for oxidation (Wang et al., 2020

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But they're also the format with the thinnest safety data and the most reported harm, which is exactly why regulators have singled them out

Sticking closely to the recommended schedule helps minimize gastrointestinal distress