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It also helps reduce the amount of sugar produced by your liver, which helps control blood sugar levels
Potenza MA, Nacci C, De Salvia MA, Sgarra L, Collino M, Montagnani M
Eur J Biochem 214:829835 Seino Y, Fukushima M, Yabe D (2010) GIP and GLP-1, the two incretin hormones: similarities and differences
We therefore conclude that before the place of GLP-1/glucagon co-agonists within the therapeutic armamentarium can be defined, future research efforts need to address the following outstanding questions: What is the optimal balance and receptor potency of GLP-1 and glucagon in a long-acting co-agonist, to minimise adverse effects and to optimise efficacy ( Figure 2 )
Linagliptin improved cell function with different efficacies in normal and diabetic islets Next we examined whether linagliptin affected glucose-stimulated insulin secretion (GSIS), a key feature of cell function, in human islets of different diabetic conditions
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