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(2018), showed that it is not possible to conclude whether DPP-4 inhibitors were associated with an increased risk of site-specific cancer including TC
The clinical efficacy is comparable: the OASIS 4 trial showed 13.6% weight loss with the oral 25 mg tablet versus 14.9% for the injection in STEP 1
[11] Frye RE
Peak headache frequency occurs during weeks one through three, then decreases substantially
GLP-1 modulates actin polymerization, improving insulin sensitivity and glucose-stimulated insulin secretion Chronic hyperglycemia, or glucotoxicity, causes pancreatic cell dysfunction, diminished glucose-stimulated insulin secretion, and the production of long actin stress fibers 6,7