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Obesity is a complex disease involving excessive amounts of body fat
Findings like that are useful as a signpost for the next study, not as proof
Rapid weight loss reduces bone mineral density
By contrast, under nutrient-depleted or amino acid starvation conditions, intracellular glutathione levels progressively decline, thereby lowering the execution threshold for GPX4 inhibition-induced ferroptosis
While a number of mechanisms including vascular, myocardial, renal, and central nervous system pathways have been suggested in animal studies, these mechanistic pathways have not been sufficiently detailed in humans and it is unclear if the same pathways are operational
