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Specifically, NRF2 is a transcription factor that governs the antioxidant pathway by targeting GSH metabolism-related genes

The FDAs decision follows an advisory committee vote that went against Novos application

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The approval covers a combination regimen of Akeega with prednisone and is based on data from the Phase III MAGNITUDE study, a randomized, double-blinded and placebo-controlled trial with 765 participants

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