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Important Safety Information : Tirzepatide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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Continue tirzepatide at 5mg weekly (first escalation)

Iranian Journal of Nursing and Midwifery Research, 15 (Suppl 1), 401-405

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In the SURMOUNT-5 trial, which directly compared the two, Mounjaro produced a 20.2% weight loss, compared with 13.7% for semaglutide 2.4 mg over 72 weeks