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Furthermore, by observing two colonies of NOD mice with different incidence rates of diabetes, it was possible to notice that the colony of NOD mice with a low incidence of T1D presented a greater abundance of A

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These studies suggest that with aging, the presence of the E4 allele may contribute to alterations in the L-carnitine bioenergetic system and to the generation of L-carnitine metabolites that could have detrimental effects on the vascular system

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