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Common Initial Tests Complete blood count (CBC) with platelet count to detect thrombocytopenia

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Statistical analysis To determine statistical significance, comparisons between two groups were performed using an unpaired Students t-test, comparisons between multiple groups were performed using a one-way ANOVA, comparisons between two or multiple groups with additional treatment conditions or repeated measurements at different time periods were performed using a two-way ANOVA, and detailed statistical analyses of high-throughput sequencing are described in the Materials and Methods section

Pyridoxal phosphate (PLP) is integral to one-carbon metabolism, a series of biochemical reactions necessary for the synthesis of nucleotides and other molecules essential for DNA and RNA production (18, 57, 58)

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