Research shows cellular responses at picomolar to nanomolar ranges, meaning effective concentrations can be measured in billionths of a gram
The Journal of Clinical Investigation
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Clinical applications might include both acute ligament injuries and chronic ligamentous laxity or instability, though human efficacy data is needed to validate these potential indications
These beneficial effects may be due to the formation of detour circuitswhich encompass spared tissue surrounding the lesionand could reconnect locomotor circuits [69], thus enabling afferent inputs to be processed and conveyed to the cortex [73] and improving spinal reflexes, even below the injury [74]
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