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60 Thus, 100 ng/ml of insulin increased proliferation rates of human breast, colon, prostate and bladder cancer cell lines in a glucose-dependent manner, achieving 744% higher proliferation when combined with diabetogenic glucose concentrations of 11 mm compared with glucose concentrations of 5.5 mm without added insulin

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GLP-1 and exendin-4 can enter the brain (34), and it has been widely assumed that GLP-1 and related peptides cross the BBB

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Curr Diagn Pathol