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Tirzepatide (Mounjaro, Zepbound) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management and chronic weight management in adults with obesity or overweight with weight-related comorbidities

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Many titration schedules increase to 12 mg over 8-12+ weeks, though some trial arms used faster or slower steps

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