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A particular relationship was established with the NO-system, and the advantage of the BPC 157 over the corresponding standard agents (i.e., corticosteroids, sulfasalazine, H2 blockers, anticholinergics, and proton pump inhibitors) which showed only weak, if any, effect on these fistulas closing (Klicek et al., 2008
& Bertram, A
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Animal studies suggest BPC-157 may significantly reduce levels of pro-inflammatory cytokines including TNF-alpha and interleukin-6, while supporting anti-inflammatory mediator activity
In particular, [1- 13 C]DHA, a 13 C enriched version of dehydroascorbic acid, has been studied with hyperpolarized (HP) 13 C magnetic resonance (MR) in preclinical models of cancer, diabetes, acute kidney injury, and fatty liver disease 15,16,17,18,19,20
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