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In July 2024, the National Institutes of Health (NIH) published a study comparing the effects of cinnamon to those of metformin, a commonly prescribed medication for managing insulin resistance in women with PCOS

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The down-regulation of IL-1 and TGF-, coupled with the restoration of the MMP-9/TIMP-1 balance, indicates the suppression of fibroblast activation and extracellular matrix remodeling