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The clearest guidance comes from injection science more broadly
Enkephalins are the physiological ligands of opioid receptors, and apart from their role in pain perception, they may benefit mood and reduce stress when upregulated [11]
Increased Levels of Neurotransmitters: The medication increases neurotransmitters such as norepinephrine, serotonin, and dopamine
If you are worried the shot will be painful you can rest assured that most clients find the discomfort negligible
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Diabetologia 52 , 271280 (2009)
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