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This is also where the supply-versus-stability point from the reconstitution section bites: if a reconstituted 10 mg vial holds ~66 doses but the solution is only reliably stable for a few weeks, plan the reconstitution volume so you are not left discarding drug you paid for

Rare side effects of B12 shots (require medical attention) Serious reactions to B-12 shots are uncommon, but its important to be aware of them: Allergic reaction, including rash, hives, dizziness, or trouble breathing Significant swelling, pain, or warmth that worsens at the injection site Palpitations or chest discomfort Signs of drug interactions, especially if you take multiple prescription medications If you experience symptoms that feel intense, progressive, or unusual, you should contact your provider right away

Methylcobalamin should not be used in patients with early hereditary optic nerve atrophy (Lebers disease)

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