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The primary function of GSH is to maintain the redox potential of the cell, which is directly connected to GSH concentration, and to prevent cellular damages caused by reactive oxygen species or toxic heavy metals
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Reyes ST, Deacon RM, Guo SG, Altimiras FJ, Castillo JB, van der Wildt B, et al
Recent studies have shown that increased ROS production promotes reversible uncoupling of NO synthase (NOS) and shifting the enzyme activity to produce more ROS instead of NO [51], [52]
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