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DOI: 10.1038/s41467-026-72861-3 Pilot study of epigenetic aging and treatment response to semaglutide in the SLIM LIVER study by Michael J
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Adipose Tissue Biology and Fat Metabolism Research Tirzepatides GIPR component adds direct adipose tissue biology to GLP-1R-mediated metabolic effects GIPR is expressed on adipocytes, and GIPR agonism has been characterised as modifying adipocyte lipid storage, lipid mobilisation, and adipokine secretion in ways that contribute to the net fat mass reduction profile of Tirzepatide
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