Consumers using weight-loss drugs tend to have reduced appetite and may dine out less frequently
Because of that, its now prescribed off-label to millions of people looking to reach a healthier weight
The SGLT2i treated cohort experienced higher rates of diabetic ketoacidosis (DKA) (RR 2.08 [95% CI 1.05, 4.12] p =0.0309) and urinary tract infection/pyelonephritis (RR 2.27 [95% CI 1.12, 4.55] p =0.019) compared with the GLP-1 RA treated cohort
"In concert with the cardiovascular benefits previously shown with semaglutide, we now have in one agent a medication that will make people feel better and live longer." "I cannot tell you, as a vascular physician, how hard it is to explain to patients that we are treating their legs to reduce the risk of a heart attack
Best Pract Res Clin Obstetrics Gynaecology
A "Strong" rating indicates support from multiple well-designed trials, "Moderate" suggests promising but less consistent findings, and "Limited" or "Emerging" applies to areas with early-stage, small, or mixed research