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Another cause of B12 deficiency is its impaired absorption in the gut, in such conditions as pernicious anemia, Crohns disease, celiac disease or surgeries that involve gastric bypass, and result in the lack of intrinsic factor

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It works by attaching to IGF-1 receptors on cells, which then activate key internal cell pathways, including PI3K-Akt and MAPK

Tyrosine hydroxylase is the critical enzyme in the synthesis of epinephrine, norepinephrine and dopamine, and tryptophan hydroxylase is the essential enzyme in the synthesis of serotonin

Patients who were obese and took semaglutide were about seven times more likely to develop NAION than those on other medications

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