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if storage of reconstituted material is necessary, aliquot into single-use volumes and keep at -80 C to minimize freeze-thaw degradation

Chronic stress and alcohol abuse may also indirectly affect B12 levels

and McGinnis, J

When B12 levels are insufficient, this protective coating can deteriorate, leading to improper nerve function and ultimately nerve damage

If not recently tested, we may order a blood test to confirm low B12 levels

[2] When to Seek Further Medical Advice About B12 Patients should maintain regular contact with their GP or healthcare team throughout B12 treatment, but certain situations warrant urgent medical review