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Neurosci Biobehav Rev 2013;37:109-122.

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ONOO-is produced by cells that contain NOS enzymes, such as smooth muscle or endothelial cells, as well as by stimulated leukocytes during an inflammatory response

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This has led medical professionals to explore the use of GLP-1 medications (glucagon-like peptide-1 agonists), which are currently FDA-approved for diabetes control, weight management, and reducing cardiovascular risks