Cardiovascular events and PsD A meta-analysis of 11 studies reported a 43% increased risk of CV diseases in PsA patients compared to the general population, with elevated risks of myocardial infarction (68%), cerebrovascular disease (22%), and heart failure (31%) [64]
Novo Nordisk (Present Leader - Semaglutide Portfolio) CagriSema Mechanism: GLP-1 + Amylin agonist Stage: Phase 3 Expected filing: 2026 Weight loss: ~22-23% in trials Amycretin Mechanism: GLP-1 + Amylin Route: injectable + oral research Stage: Phase 2 Next-gen Oral GLP-1 programs Partnership with biotech firms to develop new oral obesity drugs 2
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Weight Watchers clinic members could get Wegovy at a discounted price of $299 until July 31, 2025
Retatrutide hits 28% weight loss in Phase 3 A summary of the interesting content that I consumed this past week What I Read This Week: a summary of the content that I consumed this past week Caught My Eye 1) Retatrutide hits 28% weight loss in Phase 3 On May 21, Eli Lilly released Phase 3 results for retatrutide from the 2,339-patient TRIUMPH-1 obesity trial