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Patients often ask a smarter question than it first appears: do GLP-1 medications reduce inflammation, or do they mainly help with weight loss and blood sugar while inflammation improves as a side effect

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The post lists personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, and severe pancreatitis as contraindications to GLP-1 medications

Less common but more serious risks include: Pancreatitis, which can cause severe abdominal pain and may require stopping the medication Gallbladder problems, such as gallstones or inflammation, especially with higher doses or longer use Allergic reactions, including swelling or difficulty breathing, which need immediate medical attention Injection site reactions, such as redness or itching, with injectable forms Rare vision changes or worsening diabetic eye disease, especially when blood sugar improves rapidly Anyone with intense abdominal pain, signs of dehydration (such as dizziness or reduced urination), or unexpected vision changes should seek medical advice promptly

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Oral Wegovy 25 mg (oral semaglutide): around 12 to 15% average weight loss at the higher dose in the OASIS programme