Ralph DeFronzo," a real and highly respected endocrinologist at UT Health San Antonio who has published extensively on diabetes and insulin resistance
patients assigned to the trehalose group showed significantly higher levels of FBS and HbA 1c than those in the sucrose group (FBS, p = 0.02 and HbA 1c , p = 0.04, respectively)
and (iii) stimulation of adrenal androgen production (e.g., androstenedione and DHEAS), further augmenting the systemic androgen load (61)
Among these compounds, colladin exhibited the most potent inhibitory activity against AChE, hCA I, and hCA II, with IC50 values of 8.25 nM, 28.90 nM, and 43.31 nM, respectively
SARS-CoV-2 infection exacerbates this metabolic imbalance and predisposes these patients to the severe pathophysiologies of COVID-19, including the involvement of NETs (neutrophil extracellular traps) and HA overproduction in the lung
Link Nagano, M., Shimizu, K., & Kondo, R