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Offering both injectable and oral options, semaglutide works by mimicking the GLP-1 hormone, reducing appetite, and promoting sustainable weight loss
Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity
The most common are gastrointestinal: Nausea the most frequently reported side effect, especially during dose increases Vomiting less common than nausea, but can occur during titration Diarrhea typically mild and temporary Constipation some patients experience this instead of or in addition to diarrhea Decreased appetite this is both a therapeutic effect and something patients notice as a side effect These side effects are generally most noticeable in the first few weeks of treatment or after a dose increase, and tend to improve as the body adjusts
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Thus, Bcl2-family proteins control mitochondrial integrity, regulate cytochrome c release and intrinsic apoptosis (Youle and Strasser, 2008)
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