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SCFAs mediate some of their biological effects via the G protein-coupled receptors FFA2 and FFA3, and there has been increased interest recently in the beneficial role of FFA2 in gastrointestinal physiology and immune function, as well as in energy and glucose homeostasis
Beyond 6 months, long-term metabolic changes support continued weight reduction and improved weight maintenance
Dipeptidyl peptidase 4 (DPP-4) inhibitors for the treatment of type 2 diabetes mellitus
Patients with HbA1c levels of less than 7% lost 9.4% body weight as compared to 5.8% in those with HbA1c levels exceeding 7%
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