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Medication Adherence in the Real World In controlled trials, participants are closely monitored and encouraged to stay on their medication regimen
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10.1161/CIRCRESAHA.116.309006 173
The TRIUMPH-4 population (obesity + knee osteoarthritis) may have elevated baseline susceptibility due to existing nerve compression from joint inflammation
The first few months on tirzepatide can be an adjustment period
While fiber is important for digestion, too much can overstimulate the gut
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