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Challenges of insulin therapy include weight gain, the need for education and titration for optimal efficacy, risk of hypoglycaemia, the need for regular glucose monitoring, and cost

By binding to GLP-1 receptors, these medications enhance glucose-dependent insulin secretion from pancreatic beta cells, suppress inappropriate glucagon release, slow gastric emptying, and promote satiety through central nervous system pathways

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In April 2023, KFF fielded a survey to a nationally representative sample of 1,479 adults in the United States from the SSRS Opinion Panel to obtain population estimates of GLP-1 agonist knowledge, attitudes, and use (Montero et al., 2024)

Bock A (2024)