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Methods C57BL/6J mice and Sirt1 +/ mice were treated with exenatide (24 nmol/kg) or an NaCl solution (154 mmol/l) control i.p

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The first dose is usually 1000 mcg (1 mg)

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TR Floxed exhibited normal body weight, food intake, glucose, and insulin levels as compared to TR +/+ mice

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