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The gradual dose escalation used in trials is clinically important it is designed to reduce the incidence and severity of nausea, vomiting, and other gastrointestinal adverse effects that are common with this class of medication
Next was the three-chamber test that was crucial for evaluating social behavior and was divided into two distinct phases.This was followed by phase 1, sociability that included a testing apparatus consisting of a 60 cm x 40 cm Plexiglas box with three interconnected chambers
Topamax may cause side effects such as tingling, stomach discomfort, or taste changes
Method-of-use patents (also called indication patents) cover specific therapeutic applications or dosing regimens
doi: 10.1007/s10753-020-01189-x 273 ZhongSOuyangQZhuDHuangQZhaoJFanMet al
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