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This can be injected 1-2 days a week safely
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But they were built for different goals and different audiences
Reported side effects in trials include: Nausea Vomiting Diarrhea Constipation Reduced appetite Mild heart rate increase These are similar to other GLP-1based medications
Cota D, Matter EK, Woods SC, Seeley RJ
For patients with hepatic impairment who are often on multiple medications metabolized by CYP pathways, this lack of interaction potential is a practical advantage
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The tirzepatide niacinamide formulation and the tirzepatide with B12 combination each have their own considerations
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