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95,96 8-oxoG can mispair with adenine and therefore leads to GT mutations during DNA replication

In addition, the high expression of NRF2 enhances the expression of downstream SOD1, an important antioxidant enzyme that plays a crucial role in protecting cells from oxidative damage [36]

Vitamin B12 deficiency can cause pernicious anemia, fatigue, and nerve damage

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Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis

Low vitamin B12 can be linked to diet, problems absorbing the vitamin, certain medicines, surgery or other medical conditions