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As a result of dysfunctional Wfs1 protein, all the main symptoms found in human were present in the Wfs1 transgenic rat, including endoplasmatic reticulum (ER) stress in the medulla, increased extraparenchymal space (EPS) around the medulla, and decreased medullary volume, with the largest decreases at the level of the inferior olive 6
It acts as a primary regulator of cell migration and tissue structure throughout the body
KD is more effective than several novel anticonvulsant medications and families of affected children accept it because of its tolerability as well as its efficiency 3
Clinicians and patients alike should focus on what is firmly supported by evidence while maintaining healthy skepticism toward uses that have not yet been proved
The use of cyclosporine in dermatology: part I
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