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Jin G, Kataoka Y, Tanaka M, et al

Yes, often they do

TB500 vs BPC-157: Which One Is Right For You

Nature 565 , 312317 (2019)

These findings highlight the importance of maintaining continuous GLP-1 treatment to sustain cardiovascular benefits and indicate that strategies to reduce treatment discontinuity should be developed to maximize the cardioprotective effects of GLP-1s