Regarding treatment strategies, it is suggested that the marked decrease in GPx1 expression may be the major mechanism of tumor sensitization to anthracyclines [93] and that GPx1 can partially inhibit doxorubicin-induced cell death-related signaling in breast cancer by interfering with the activation of the sphingomyelin-ceramide pathway [85]
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Company announcement: Novo Nordisk A/S: Wegovy pill approved in the US as first oral GLP-1 for weight management
One study found that high doses of oral B12 (1,000 mcg daily) could provide adequate absorption even in the presence of intrinsic factor deficiency
Corresponding author: Servicio de Cardiologa, Hospital Universitario de Canarias, Ofra s/n, 38320 La Cuesta, La Laguna, Santa Cruz de Tenerife, Canarias, Spain