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It is the predominant intracellular non-protein thiol in mammalian tissues, present at concentrations typically ranging from 110 mM in the cytosol, with particularly high concentrations in the liver (up to 10 mM), which is the primary site of GSH synthesis and export

however, in a previous interim analysis, the authors reported that a protective effect was perceived more clearly in female individuals than in male individuals [107]

Naldi et al., 2020

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